The meaning of the Acronym MUFF is...

MUFF is

• Error, in Baseball
• Manchester United Football Fan

More Meanings For MUFF:

• Melbourne Underground Film Festival
• Error, in Baseball
• Manchester United Football Fan
• Mandatory Ugly Fat Friend
• Many United For Feminism
• Major Undiscovered Female Fluff

MUFF is also in:

• Chat
• Funnies
• Media
• Sports