The meaning of the Acronym MLB is...

MLB is

• Melbourne, Florida USA

More Meanings For MLB:

• Multi-Layer Board
• Material, Labor, Burden
• Murphys Law Baseball
• Major League Baseball
• Maple Leaf Baseball
• Middle Line Backer
• Macro library file (Symphony)
• Major Logic Board
• Multilayer Board
• Mini Landbridge
• MINURSO Logistic Base
• "Mike" LineBacker (Middle LineBacker)
• Massive Legal Budget
• Millionaires League Baseball
• Major League Bonds

MLB is also in:

• Accounting
• Electronics
• File Extensions
• General
• Law
• NASA
• NFL Teams
• Sports
• Transportation
• Unfiled
• United Nations